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Although only three of 16 participants were female participants in the Older (postmenopausal age) group, existing literature indicates that gut microbiome characteristics differ substantially between sexes, with women typically exhibiting greater microbial richness than men ( n = 44) and men ( n = 42) that were considerably less pronounced between postmenopausal women ( n = 45) and men ( n = 48) ( cai and gbu gene clusters), such that the change in abundance before and after the OCC can be compared between the pomegranate and placebo interventions

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miR-29c-3p promotes alcohol dehydrogenase gene cluster expression by activating an ADH6 enhancer

Front Pharmacol 15:1405446